132887-08-2Relevant academic research and scientific papers
A method for synthesizing arabinosyladenosine (by machine translation)
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Paragraph 0019; 0025; 0027; 0031; 0033, (2018/04/01)
The invention discloses a method for synthesizing arabinosyladenosine method, which belongs to the field of nucleoside in organic chemistry synthesis. The reaction steps are as follows: in order to adenosine as raw material, in a catalytic amount of dibutyl tin oxide or borate and under the action of the nitrobenzene sulfonyl chloride reaction, to obtain the 2 '- to the nitrobenzene sulfonyl protecting adenosine, then under the action of the potassium acetate and catalyst, undergo the substitution reaction to obtain the 2' - acetyl arabinosyladenosine, finally ammonolysis to obtain arabinosyladenosine. The synthesis method cheap raw materials, the step is short, easy to industrial production, with the actual application prospect. (by machine translation)
