13290-00-1 Usage
Uses
N-(2-Furoyl)glycine Methyl Ester is an intermediate in synthesizing 2-Furoylglycine (F865225), which is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection.
Check Digit Verification of cas no
The CAS Registry Mumber 13290-00-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,2,9 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13290-00:
(7*1)+(6*3)+(5*2)+(4*9)+(3*0)+(2*0)+(1*0)=71
71 % 10 = 1
So 13290-00-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO4/c1-5(8(11)12)9-7(10)6-3-2-4-13-6/h2-5H,1H3,(H,9,10)(H,11,12)
13290-00-1Relevant articles and documents
Furan- and thiophene-2-carbonyl amino acid derivatives activate hypoxia-inducible factor via inhibition of factor inhibiting hypoxia-inducible factor-1
Kawaguchi, Shin-ichi,Gonda, Yuhei,Yamamoto, Takuya,Sato, Yuki,Shinohara, Hiroyuki,Kobiki, Yohsuke,Ichimura, Atsuhiko,Dan, Takashi,Sonoda, Motohiro,Miyata, Toshio,Ogawa, Akiya,Tsujita, Tadayuki
, (2018)
Induction of a series of anti-hypoxic proteins protects cells during exposure to hypoxic conditions. Hypoxia-inducible factor-α (HIF-α) is a major transcription factor that orchestrates this protective effect. To activate HIF exogenously, without exposing