132901-31-6

Basic information

• Product Name: [1,1'-Biphenyl]-2,2'-dicarboxaldehyde, 4,4'-dimethoxy-
• CAS NO: 132901-31-6
• Molecular Formula: C16H14O4
• Molecular Weight: 270.285
• Mol File: 132901-31-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [1,1'-Biphenyl]-2,2'-dicarboxaldehyde, 4,4'-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Biphenyl]-2,2'-dicarboxaldehyde, 4,4'-dimethoxy-(132901-31-6)
• EPA Substance Registry System: [1,1'-Biphenyl]-2,2'-dicarboxaldehyde, 4,4'-dimethoxy-(132901-31-6)

Safety Data

• Hazardous Substances Data: 132901-31-6(Hazardous Substances Data)

Upstream product

• 93-02-7 2,5-dimethoxybenzaldehyde 
• 1458-98-6 2-methyl-3-bromo-1-propene 
• 139962-95-1 2-formyl-4-methoxyphenylboronic acid 
• 62113-90-0 2-oxo-2H-chromen-4-yl methanesulfonate 
• 77287-58-2 2-iodo-5-methoxybenzaldehyde 

Relevant articles and documents

Nickel-catalyzed cross-coupling reactions of 4-mesylcoumarins with aryl halides: Facile synthesis of 4-substituted coumarins

A new and efficient nickel-catalyzed cross-coupling reaction between 4-mesylcoumarins and aryl halides was developed to give a number of 4-arylcoumarins in good yield under mild conditions. Unlike the previously reported coupling examples, this new method allows the direct cross-coupling of 4-mesylcoumarins with aryl- or vinyl halides in the NiCl2(PPh 3)2/PPh3/Zn/toluene system. This has greatly facilitated the synthesis of biologically useful 4-substituted coumarins.

Intramolecular carbonyl-ene reactions in the synthesis of peri-oxygenated hydroaromatics

2-Methallyl aromatic aldehydes, synthesized by Suzuki coupling of 2-formylphenylboronic acids, are shown to provide cycloalkylidene ene products under acidic conditions. Susceptibility of the products to aromatization is manoeuvred by varying the reaction conditions and catalysts including binol-derived Br?nsted acid catalysts. A peri-effect is identified as a controlling factor for the aromatizations. Several oxidative transformations of an ene product are carried out as model studies of hydroaromatic polyketide natural products.