62113-90-0

Usage

Uses

Used in Organic Synthesis:
2-oxo-2H-chromen-4-yl methanesulfonate is used as a reagent in organic synthesis for the functionalization of aromatic compounds. Its ability to undergo nucleophilic aromatic substitution reactions makes it a valuable tool for the synthesis of various complex organic molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-oxo-2H-chromen-4-yl methanesulfonate is used as a key intermediate in the synthesis of various pharmaceuticals and biologically active molecules. Its unique chemical properties allow for the development of new drugs with potential therapeutic applications.
Used in Research and Development:
2-oxo-2H-chromen-4-yl methanesulfonate is also utilized in research and development for the exploration of new chemical reactions and the discovery of novel compounds with potential applications in various fields, including medicine, agriculture, and materials science. Its versatility as a reagent makes it an essential component in the development of new synthetic methodologies and the synthesis of innovative molecules.

Upstream product

• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 1135539-10-4 1-(methylsulfonyl)-4-phenyl-1H-1,2,3-triazole 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1309975-00-5 4-(4-methoxybenzoyl)-2H-chromen-2-one 
• 15185-05-4 4-phenylcoumarin 
• 132901-31-6 4,4′-dimethoxy[1,1′-biphenyl]-2,2′-dicarbaldehyde 
• 118545-81-6 4,4'-bis-(2H-chromen-2-one) 

Relevant academic research and scientific papers

Coumarin sulfonates: As potential leads for ROS inhibition

Coumarin sulfonates 4–43 were synthesized by reacting 3-hydroxy coumarin 1, 4-hydroxy coumarin 2?and?6-hydroxy coumarin 3 with different substituted sulfonyl chlorides and subjected to evaluate for their in vitro immunomodulatory potential. The compounds

Transition metal- and oxidant-free sulfonylation of 1-sulfonyl-1H-1,2,3-triazoles to enols for the synthesis of sulfonate derivatives

A novel and convenient protocol for the synthesis of sulfonate derivatives via DABCO-catalyzed direct sulfonylation of 1-sulfonyl-1,2,3-triazoles to different enols has been established. This synthetic route could effectively avoid the use of transition m

Coumarin-4-sulfonate derivatives and preparation method thereof

The invention discloses coumarin-4-sulfonate derivatives and a preparation method thereof. The structure of the coumarin-4-sulfonate derivatives is shown as formula (I) in the description, wherein R1is selected from H, C1-C5 alkyl or C1-C5 alkoxy; R2 is s

Chromatography-Free and Eco-Friendly Synthesis of Aryl Tosylates and Mesylates

Two chromatography-free and eco-friendly protocols have been developed to synthesize aryl tosylates and mesylates by the tosylation and mesylation of the corresponding hydroxyarenes, respectively. These protocols are superior to other known ones regarding

Inhibition of reverse transcriptase and Taq DNA polymerase by compounds possessing the coumarin framework

Coumarin derivatives were prepared using natural products isolated from plants belonging in the Pterocaulon genus (Asteraceae) and commercial drugs. Some molecules have displayed interesting activity against myeloid murine leukemia virus-reverse transcriptase (MMLV-RT) (compounds 20 and 28 produced inhibition with IC50 values of 38.62 and 50.98 μM, respectively) and Taq DNA polymerase (analogues 13 and 14 produced inhibition with IC 50 values of 48.08 and 57.88 μM, respectively). Such inhibitors may have importance as antiretroviral chemotherapeutic agents and also in the development of anticancer drugs.

Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use

This invention relates to novel coumarin derivative, formulations comprising same, and to methods of making and using these compounds and formulations, which are useful as repellents against insects and/or pests. The compounds also prevent illness and disease caused by insect/pest-borne vectors, and provide safer, more effective alternatives to existing repellents.