132902-38-6Relevant academic research and scientific papers
Homochiral Amine Oxides in the Enantioselective Reduction of Ketones
O'Neil, Ian A.,Turner, Carl D.,Kalindjian, S. Barret
, p. 777 - 780 (1997)
The synthesis of a number of novel homochiral prolinol N-oxide derivatives is described. Several of these were found to catalyse the borane reduction of α-chloroacetophenone to (S)-2-chloro-1-phenylethanol in excellent chemical yield and in 96% ee.
CHIRAL LIGANDS CONTAINING HETEROATOMS. 6. 1-(2-PYRIDYLMETHYL)PYRROLIDINE IN THE CHIRAL CATALYSIS OF ADDITION OF DIETHYLZINC TO BENZALDEHYDE
Chelucci, Giorgio,Falorni, Massimo,Giacomelli, Giampaolo
, p. 843 - 849 (2007/10/02)
The synthesis of a series of new optically active pyridine ligands from proline derivatives has been developed for the enantioselective addition of dialkyl zinc compounds to aldehydes.The results obtained indicate that the corrdination of a metal atom to the nitrogen of the pyridine ring is essential in determining the stereochemistry of the process.
