Synlett p. 777 - 780 (1997)
Update date:2022-07-30
Topics:
O'Neil, Ian A.
Turner, Carl D.
Kalindjian, S. Barret
The synthesis of a number of novel homochiral prolinol N-oxide derivatives is described. Several of these were found to catalyse the borane reduction of α-chloroacetophenone to (S)-2-chloro-1-phenylethanol in excellent chemical yield and in 96% ee.
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