1329034-42-5

Basic information

• Product Name: 4-methyl-N-((1-methyl-1H-indol-3-yl)methyl)benzenesulfonamide
• Synonyms: 4-methyl-N-((1-methyl-1H-indol-3-yl)methyl)benzenesulfonamide
• CAS NO: 1329034-42-5
• Molecular Weight: 314.408
• Mol File: 1329034-42-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-((1-methyl-1H-indol-3-yl)methyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-((1-methyl-1H-indol-3-yl)methyl)benzenesulfonamide(1329034-42-5)
• EPA Substance Registry System: 4-methyl-N-((1-methyl-1H-indol-3-yl)methyl)benzenesulfonamide(1329034-42-5)

Safety Data

• Hazardous Substances Data: 1329034-42-5(Hazardous Substances Data)

Upstream product

• 19012-03-4 N-methyl-3-formylindole 
• 70-55-3 toluene-4-sulfonamide 
• 100-61-8 N-methylaniline 
• 941-55-9 4-toluenesulfonyl azide 
• 62-53-3 aniline 
• 14465-74-8 N-phenyl-N-prop-2-ynylamine 
• 4282-82-0 N-methyl-N-propargylaniline 
• 1616405-21-0 N-methyl-N-((1-tosyl-1H-1,2,3-triazol-4-yl)methyl)benzenamine 

Relevant articles and documents

Scope of the Reactions of Indolyl- and Pyrrolyl-Tethered N-Sulfonyl-1,2,3-triazoles: Rhodium(II)-Catalyzed Synthesis of Indole- and Pyrrole-Fused Polycyclic Compounds

An efficient synthesis of tetrahydrocarboline-type products and polycyclic spiroindolines has been achieved. The transformation proceeds via rhodium(II)-catalyzed intramolecular annulations of indolyl- and pyrrolyl-tethered N-sulfonyl-1,2,3-triazoles. The reaction could be tuned toward either the formal [3 + 2] cycloaddition or the C-H functionalization reaction depending on the electronic and structural features of the substrates, leading to the production of a variety of structurally related heterocyclic compounds.

Synthesis of substituted 3-indolylimines and indole-3-carboxaldehydes by rhodium(II)-catalyzed annulation

An efficient Cu/Rh-catalyzed method is proposed for the synthesis of 3-indolylimines from N-propargylanilines through Rh(II)-catalyzed denitrogenative annulation of N-sulfonyl-1,2,3-triazoles. Further combined with hydrolysis or reduction, a one-pot method is developed to enable the direct incorporation of an imine, aldehyde, or amine group into an indole system from an alkyne. A variety of substituted 3-indolylimines, indole-3-carboxaldehydes, and 3-Indolylmethanamines are synthesized in good yields.