132906-06-0

Basic information

• Product Name: 4-METHYL-PIPERAZINE-1-CARBOXYLIC ACID PHENYL ESTER
• Synonyms: 4-METHYL-PIPERAZINE-1-CARBOXYLIC ACID PHENYL ESTER
• CAS NO: 132906-06-0
• Molecular Formula: C₁₂H₁₆N₂O₂
• Molecular Weight: 220.27
• Mol File: 132906-06-0.mol

Chemical Properties

• Boiling Point: 320.1°C at 760 mmHg
• Flash Point: 147.4°C
• Appearance: /
• Density: 1.148g/cm³
• Vapor Pressure: 0.000325mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 4-METHYL-PIPERAZINE-1-CARBOXYLIC ACID PHENYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-PIPERAZINE-1-CARBOXYLIC ACID PHENYL ESTER(132906-06-0)
• EPA Substance Registry System: 4-METHYL-PIPERAZINE-1-CARBOXYLIC ACID PHENYL ESTER(132906-06-0)

Safety Data

• Hazardous Substances Data: 132906-06-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16N2O2/c1-13-7-9-14(10-8-13)12(15)16-11-5-3-2-4-6-11/h2-6H,7-10H2,1H3

Upstream product

• 109-01-3 1-methyl-piperazine 
• 35180-03-1 chloromethyl phenyl carbonate 
• 1885-14-9 phenyl chloroformate 
• 108-95-2 phenol 

Downstream Products

• 88701-65-9 4-methyl-piperazine-1-carboxylic acid hydrazide 
• 14052-80-3 4-methyl-piperazine-1-carboxylic acid (5-nitro-furan-2-ylmethylene)-hydrazide 

Relevant articles and documents

AZAARENE DERIVATIVES

A compound represented by the general formula: wherein X1 represents a nitrogen atom or a group represented by the formula -CR10=; X2 represents a nitrogen atom or a group represented by the formula -CR11=; Y represents an oxygen atom or the like; R1 represents a C1-6 alkoxy group, an optionally substituted C6-10 aryloxy group, a group represented by the formula -NR12aR12b or the like; R2 represents a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like; R3, R4, R5, R6, R7, R8, R10 and R11 each independently represent a hydrogen atom, a halogen atom, an optionally substituted C1-6 alkyl group, or the like; R9 represents a group represented by the formula -NR16aR16b or the like; and R12a, R12b, R16a and R16b each independently represent a hydrogen atom, an optionally substituted C1-6 alkyl group, or the like, a salt thereof, or a hydrate of the foregoing.

Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives

Several novel semicarbazones derivatives were prepared from 5-nitro-2-furaldehyde or 5-nitrothiophene-2-carboxaldehyde, and tested in vitro as potential anti-trypanosomal agents. The compounds were prepared in good to excellent yields in 2-3 steps from readily available starting materials. Some derivatives were found to be active against Trypanosoma cruzi with an activity similar to that of Nifurtimox.

α-Haloalkyl Haloformates and Related Compounds 1. A Convenient Synthesis of Carbamates via Chloromethyl Carbamates

The preparation of carbamates under mild conditions utilizing a new class of activated carbonates (containing chloromethyl function) is described.