132930-88-2Relevant academic research and scientific papers
Phosphorylated derivatives of L-dopa and compositions and methods for increasing the melanin content in mammalian skin and hair
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, (2008/06/13)
A phosphorylated derivative of L-dopa of the formula STR1 wherein when X is STR2 wherein Z is --CH 2, N, S or a linkage other than oxygen which renders the phosphate group resistant to hydrolysis by phosphatase enzymes in tissues and biological fluids,then Y is OQ, wherein Q is H or an alkyl with one to twelve carbon atoms, orwherein X is OQ, then Y is STR3 wherein R'' is hydrogen or a pharmaceutically acceptable cation and R is a moiety which increases hydropobicity. The phosphorylated derivative of L-dopa is useful as an agent to increase the melanin content in mammalian skin and hair.
