1329422-57-2

Basic information

• Product Name: N-methyliminodiacetyl (1-(4-fluorophenyl)-2-oxoethyl)boronate
• Synonyms: N-methyliminodiacetyl (1-(4-fluorophenyl)-2-oxoethyl)boronate
• CAS NO: 1329422-57-2
• Molecular Weight: 293.059
• Mol File: 1329422-57-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 168-173°C
• CAS DataBase Reference: N-methyliminodiacetyl (1-(4-fluorophenyl)-2-oxoethyl)boronate(CAS DataBase Reference)
• NIST Chemistry Reference: N-methyliminodiacetyl (1-(4-fluorophenyl)-2-oxoethyl)boronate(1329422-57-2)
• EPA Substance Registry System: N-methyliminodiacetyl (1-(4-fluorophenyl)-2-oxoethyl)boronate(1329422-57-2)

Safety Data

• Hazardous Substances Data: 1329422-57-2(Hazardous Substances Data)

Usage

General Description

4-Fluorophenyl-α-MIDA-boryl aldehyde is an α-MIDA (α-N-methyliminodiacetyl) boryl aldehyde derivative.

Upstream product

• 1312815-41-0 C₁₃H₁₃BFNO₄ 

Downstream Products

• 1380504-16-4 (MIDA boryl)(4-fluorophenyl)methyl isocyanate 
• 1380504-04-0 2-(MIDA boryl)-2-(4-fluorophenyl)acetic acid 

Relevant articles and documents

Access to Cyclic Amino Boronates via Rhodium-Catalyzed Functionalization of Alkyl MIDA Boronates

Herein, we describe the rhodium-catalyzed C-H amination reaction of 1,2-boryl sulfamate esters derived from amphoteric α-boryl aldehydes. Depending on the substitution pattern of the boryl sulfamate ester, a diverse range of five- or six-membered ring heterocycles are accessible using this transformation. The highly chemoselective nature of the C-H functionalization reaction preserves the alkyl boronate functional group, which enables the synthesis of B-C-N and B-C-C-N motifs that are present in a number of hydrolase inhibitors.