132950-81-3Relevant articles and documents
Studies towards the synthesis of the marine metabolite, octalactin A
Hulme, Alison N.,Howells, Garnet E.
, p. 8245 - 8248 (1997)
Studies towards the synthesis of the marine metabolite octalactin A 1, are described. Key steps in this strategy include an anti aldol reaction to set the C(r)C(s) stereochemistry, Horner Wadsworth Emmons coupling to give the trisubstituted E-double bond and a novel samarium-mediated cyclisation reaction.