132980-39-3Relevant academic research and scientific papers
Electro-oxidative C(sp3)-H Amination of Azoles via Intermolecular Oxidative C(sp3)-H/N-H Cross-Coupling
Wu, Jiwei,Zhou, Yi,Zhou, Yuchen,Chiang, Chien-Wei,Lei, Aiwen
, p. 8320 - 8323 (2017)
A method for electrooxidative C(sp3)-H amination via intermolecular oxidative C(sp3)-H/N-H cross-coupling has been developed under metal- and oxidant-free conditions. The C(sp3)-H bonds adjacent to oxygen, nitrogen, and sulfur atoms could all react smoothly with various amines to give the corresponding products with moderate to good yields (30-93%). In addition, the C(sp3)-H bonds of benzylic and allylic are also tolerated in this reaction. A preliminary mechanistic study indicates that the C-H cleavage of tetrahydrofuran is probably not involved in the rate-determining step.
Multifunctional lubricating additive and preparation method thereof
-
Paragraph 0024-0030, (2021/11/10)
The invention provides a multifunctional lubricating additive and a preparation method thereof, the chemical structural formula of the lubricating additive is I, and the lubricating additive is prepared by taking benzotriazole, formaldehyde and 2, 6-di-tert-butyl phenol as raw materials and hydrochloric acid as a catalyst through hydrothermal reaction. The multifunctional lubricating additive is added into trimethylolpropane octyl decyl ester (TMTC) to show good corrosion resistance and friction reduction and wear resistance, has an antioxidant synergistic effect when being compounded with an amine antioxidant, and is an environment-friendly lubricating additive.
Metal-free cross-dehydrogenative C–N coupling of azoles with xanthenes and related activated arylmethylenes
Li, Yanni,Li, Yanping,Li, Yuan,Chen, Chunlin,Ying, Fengyuan,Dong, Ying,Liang, Deqiang
supporting information, p. 2053 - 2065 (2019/05/29)
A metal-free C(sp3)–H/N–H cross-coupling of azoles with xanthenes and related activated arylmethylenes is presented. Both the use of azoles and the activation pattern of C(sp3)–H sources are essential for this transformation. In the
o-(α-Benzotriazolylalkyl)phenols: Versatile Intermediates for the Synthesis of Substituted Phenols
Katritzky, Alan R.,Lan, Xiangfu,Lam, Jamshed N.
, p. 1809 - 1817 (2007/10/02)
Phenols and naphthols are benzotriazolylmethylated by 1-(hydroxymethyl)-1H-benzotriazole (13) (a formaldehyde derivative) in the o- or (if both o-positions are occupied) in the p-position.The reaction can be extended to other aldehydes in the case of the naphthols.The methylene group in the o-(benzotriazolylmethyl)phenols can be lithiated (but only after trimethylsilyl protection of the hydroxy group) and then substituted by various electrophiles.The benzotriazole residues in both the primary products and in their substituted derivatives can be displaced by the alkylanions of Grignard reagents or by hydride ions allowing the elaboration of many new types of substituted phenols. Key Words: Lithiation/ Mannich reaction/ Alkylation/ Grignard reaction/ Condensation
