133010-18-1

Basic information

• Product Name: Carbamic acid, (2-fluoro-2-oxo-ethyl)-, phenylmethyl ester
• CAS NO: 133010-18-1
• Molecular Formula: C10H10FNO3
• Molecular Weight: 211.193
• Mol File: 133010-18-1.mol

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (2-fluoro-2-oxo-ethyl)-, phenylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2-fluoro-2-oxo-ethyl)-, phenylmethyl ester(133010-18-1)
• EPA Substance Registry System: Carbamic acid, (2-fluoro-2-oxo-ethyl)-, phenylmethyl ester(133010-18-1)

Safety Data

• Hazardous Substances Data: 133010-18-1(Hazardous Substances Data)

Upstream product

• 1138-80-3 N-(Benzyloxycarbonyl)glycine 

Downstream Products

• 869002-29-9 N-benzyloxycarbonylglycyl-L-4-thia-5,5-dimethylproline 
• 1212-53-9 methyl N-benzyloxycarbonylglycinate 
• 1049736-72-2 4(N),10(N)-bis-[N-(benzyloxycarbonyl)glycyl]-1,7-dimethyl-1,4,7,10-tetraazacyclododecane 
• 1058149-37-3 C₂₆H₃₉N₅O₆ 
• 869001-98-9 dibenzyl N-benzyloxycarbonyl-glycyl-L-2-allylprolyl-L-glutamate 
• 915958-44-0 dibenzyl (2S,5'R)-2-[1'-(2''-benzyloxycarbonylamino-acetyl)-8'-hydroxy-6'-oxo-1',7'-diazaspiro[4.4]non-7'-yl]-pentanedioate 
• 869001-96-7 dibenzyl N-benzyloxycarbonyl-glycyl-L-2-ethylprolyl-L-glutamate 
• 869002-11-9 dibenzyl (2S,5'R)-2-[1'-(2''-benzyloxycarbonylamino-acetyl)-6'-oxo-1',7'-diazaspiro[4.4]non-7'-yl]-pentanedioate 
• 869002-32-4 dibenzyl N-benzyloxycarbonyl-glycyl-L-4-thia-5,5-dimethylprolyl-L-glutamate 
• 869001-88-7 N-benzyloxycarbonyl-glycyl-L-2-allylproline 
• 869001-82-1 methyl N-benzyloxycarbonyl-glycyl-L-2-allylprolinate 
• 869001-87-6 N-benzyloxycarbonyl-glycyl-L-2-ethylproline 
• 869001-81-0 methyl N-benzyloxycarbonyl-glycyl-L-2-ethylprolinate 
• 869001-86-5 N-benzyloxycarbonyl-glycyl-L-2-methylproline 

Relevant articles and documents

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A new bio-inspired approach is reported for amide and peptide synthesis using α-amino esters that possess a potential activating group (PAG) at the ester residue. To activate the ester functionality under mild metal-free conditions, we exploited the facile dearomatization of phenols with hypervalent iodine(iii) reagents. Using a pyridine-hydrogen fluoride complex, highly reactive acyl fluoride intermediates can be successfully generated, thereby allowing for the smooth formation of sterically hindered amides and peptides from bulky amines and α-amino esters, respectively.

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