1330184-67-2Relevant academic research and scientific papers
Bioactive sulfoximines: Syntheses and properties of Vioxx analogs
Park, Seong Jun,Buschmann, Helmut,Bolm, Carsten
, p. 4888 - 4890 (2011/09/21)
The syntheses and biological profiles of sulfoximine-based Vioxx analogs 2 are described. Interesting data have been obtained for 2a, which shows a selective COX-2 inhibition (albeit not as strong as Vioxx itself) exhibiting reduced hERG activity compare to the parent sulfone Vioxx (1).
