133034-08-9 Usage
Uses
Used in Pharmaceutical Industry:
3-(S)-(-)-(1-carbamoyl-1,1-diphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)-2-oxoethyl]-pyrrolidine hydrochloride is used as an active pharmaceutical ingredient for the treatment of urinary incontinence. It functions by selectively blocking the M3 muscarinic acetylcholine receptor, which is involved in the regulation of smooth muscle contraction and secretion in the urinary tract.
Used in Medicinal Chemistry Research:
3-(S)-(-)-(1-carbamoyl-1,1-diphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)-2-oxoethyl]-pyrrolidine hydrochloride is also utilized in medicinal chemistry research as a starting material or a structural motif for the development of new drugs targeting various diseases. Its unique structure and functional groups make it a valuable candidate for further modification and optimization to enhance its pharmacological properties and therapeutic potential.
Used in Drug Delivery Systems:
3-(S)-(-)-(1-carbamoyl-1,1-diphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl)-2-oxoethyl]-pyrrolidine hydrochloride can be employed in the development of novel drug delivery systems. Its structural features may allow for the design of targeted drug carriers or controlled-release formulations, improving the bioavailability and therapeutic efficacy of associated drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 133034-08-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,3 and 4 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 133034-08:
(8*1)+(7*3)+(6*3)+(5*0)+(4*3)+(3*4)+(2*0)+(1*8)=79
79 % 10 = 9
So 133034-08-9 is a valid CAS Registry Number.
133034-08-9Relevant articles and documents
PREPARATION OF DARIFENACIN AND ITS SALTS
-
Page/Page column 38-39, (2008/12/08)
Provided are various processes and compounds related to darifenacin and/or its salts. For example, there is provided a process for preparing a free base of darifenacin: Formula, or the salt thereof, the process including reacting 3-(S)-(cyanodiphenylmethyl)-1-[2-(2,3-dihydrobenzofuran-5-yl) ethyl] pyrrolidine of the Formula (IV), or a salt thereof: Formula (IV) with a base effective to convert the nitrile group of the compound of the Formula (IV) to the amide group of the darifenacin in an organic solvent, the reaction being carried out in the organic solvent, with a proviso that the solvent is not 2-methyl-butan-2-ol, and with further proviso that the reaction produces less than about 0.5 % of the compound of the Formula (Ic): Formula (Ic) in the reaction mass, as measured by HPLC. Various embodiments and variants are provided.
