133036-82-5Relevant articles and documents
RING OPENING OF 2-ACYLAMINO-4,5-DIHYDRO-3-FURANCARBONITRILES BY USE OF TITANIUM (IV) CHLORIDE
Maruoka, Hiroshi,Yamagata, Kenji,Yamazaki, Motoyoshi
, p. 2011 - 2023 (2007/10/02)
The ring opening of 2-acylamino-4,5-dihydro-3-furancarbonitriles (1a-f) with titanium (IV) chloride gave the corresponding N-acyl-4-chloro-2-cyanobutanamides (2a-f).On treatment with potassium carbonate, compounds (2a-f) were converted to the corresponding N-acyl-1-cyanocyclopropanecarboxamides (3a-f).On the other hand, the reaction of 2-benzamido-4,5-dihydro-3-thiophenecarbonitriles (4a-c) with titanium (IV) chloride gave the corresponding 2-benzamido-4,5-dihydro-3-thiophenecarboxamides (5a-c).