133044-44-7

Basic information

• Product Name: 2(3H)-Benzothiazolone,6-acetyl-(9CI)
• Synonyms: 6-acetylbenzo[d]thiazol-2(3H)-one;6-Acetylbenzo[d]thiazol-2(3H);2(3H)-Benzothiazolone,6-acetyl-(9CI);6-acetyl-1,3-benzothiazole-2(3)-one
• CAS NO: 133044-44-7
• Molecular Formula: C₉H₇NO₂S
• Molecular Weight: 193.225
• EINECS: 1312995-182-4
• Product Categories: BENZOTHIAZOLE
• Mol File: 133044-44-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 190-194°C
• Appearance: /
• Density: 1.36 g/cm³
• Refractive Index: 1.635
• PKA: 9.76±0.20(Predicted)
• CAS DataBase Reference: 2(3H)-Benzothiazolone,6-acetyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Benzothiazolone,6-acetyl-(9CI)(133044-44-7)
• EPA Substance Registry System: 2(3H)-Benzothiazolone,6-acetyl-(9CI)(133044-44-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 133044-44-7(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C9H7NO2S/c1-5(11)6-2-3-7-8(4-6)13-9(12)10-7/h2-4H,1H3,(H,10,12)

Upstream product

• 934-34-9 2(3H)-Benzothiazolone 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 
• 51360-57-7 3-acetyl-2(3H)-benzothiazolone 
• 1373399-25-7 C₁₁H₁₂INO₃ 

Downstream Products

• 1426329-39-6 tert-butyl (4-bromo-2-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]thiazol-6-yl) propanamido)phenyl)carbamate 

Relevant articles and documents

Benzo[d]thiazol-2(3H)-ones as new potent selective CB2 agonists with anti-inflammatory properties

The high distribution of CB2 receptors in immune cells suggests their important role in the control of inflammation. Growing evidence offers this receptor as an attractive therapeutic target: selective CB2 agonists are able to modula

CuI-catalyzed one-pot synthesis of benzothiazolones from 2-iodoanilines-derived carbamates and sodium sulfide

A copper-catalyzed procedure was developed for assembling benzothiazolones from ethyl 2-iodophenylcarbamates and sodium sulfide. A number of functional groups, such as methoxy, acyl, amide, carboxylate, trifluoromethyl, fluoro, and chloro, were tolerated under these conditions, providing benzothiazolones in good yields.

Application of the "fries like" rearrangement using ZnCL 2 for the synthesis of 6-acyl-2(3H)-benzothiazolones

In this work we report another method of acylation on the 6-position of the 2(3H)-benzothiazolone ring with Fries-like rearrangement catalyzed by zinc chloride instead of aluminium chloride and 3-acyl-2(3H)-benzothiazolones derivatives as starting materia