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2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE is a chemical compound characterized by the molecular formula C6H3F3NOS. It is a yellow liquid known for its unique structure, which includes a thiazole ring with a trifluoromethyl group and a carbonyl group at the 4-position. 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE is recognized for its versatility in organic synthesis and medicinal chemistry, making it a valuable building block in the creation of pharmaceuticals, agrochemicals, and other biologically active compounds.

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  • 133046-48-7 Structure
  • Basic information

    1. Product Name: 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE
    2. Synonyms: 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE;2-Trifluoromethyl-4-thiazolecarboxaldehyde;2-(Trifluoromethyl)-1,3-thiazole-4-carboxaldehyde;4-Formyl-2-(trifluoromethyl)-1,3-thiazole;2-(trifluoroMethyl)thiazol-4-carbaldehyde
    3. CAS NO:133046-48-7
    4. Molecular Formula: C5H2F3NOS
    5. Molecular Weight: 181.14
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 133046-48-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 155 ºC
    3. Flash Point: 47 ºC
    4. Appearance: /
    5. Density: 1.544
    6. Vapor Pressure: 3.14mmHg at 25°C
    7. Refractive Index: 1.499
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: -2.41±0.10(Predicted)
    11. CAS DataBase Reference: 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE(133046-48-7)
    13. EPA Substance Registry System: 2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE(133046-48-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 133046-48-7(Hazardous Substances Data)

133046-48-7 Usage

Uses

Used in Pharmaceutical Industry:
2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE is used as a key intermediate in the synthesis of various pharmaceuticals for its potential to contribute to the development of new drugs with improved therapeutic properties.
Used in Agrochemical Industry:
2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE is used as a starting material in the production of agrochemicals, particularly for its pesticidal and herbicidal properties, which are crucial in enhancing crop protection and yield.
Used in Organic Synthesis:
2-(TRIFLUOROMETHYL)-1,3-THIAZOLE-4-CARBALDEHYDE is used as a versatile building block in organic synthesis for its ability to form a wide range of chemical compounds, contributing to the advancement of chemical research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 133046-48-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,0,4 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 133046-48:
(8*1)+(7*3)+(6*3)+(5*0)+(4*4)+(3*6)+(2*4)+(1*8)=97
97 % 10 = 7
So 133046-48-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H2F3NOS/c6-5(7,8)4-9-3(1-10)2-11-4/h1-2H

133046-48-7Downstream Products

133046-48-7Relevant articles and documents

2,3-SUBSTITUTED FUSED BICYCLIC PYRIMIDIN-4(3H)-ONES MODULATING THE FUNCTION OF THE VANILLOID-1 RECEPTOR (VR1)

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Page/Page column 47, (2008/06/13)

The use of a compound of formula (I): for the manufacture of a medicament for the treatment of conditions ameliorated by the modulation of the function of the vanilloid-1 receptor (VR1, also known as TRPV1).

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