1330680-41-5

Upstream product

• 954416-30-9 (4R)-4-((S)-1-(4-methoxybenzyloxy)allyl)-2,2-dimethyl-1,3-dioxolane 
• 954416-31-0 (2R,3S)-3-(4-methoxybenzyloxy)pent-4-ene-1,2-diol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 18524-19-1 (S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-prop-2-en-1-ol 
• 80532-36-1 ((2R,3S)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)oxiran-2-yl)methanol 
• 79060-23-4 (2E)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]prop-2-en-1-ol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 64520-58-7 ethyl (E)-3-((S)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate 

Downstream Products

• 1330680-39-1 (8R,5Z)-((2R,3S)-1-(tert-Butyldiphenylsilyloxy)-3-hydroxypent-4-en-2-yl) 8-hydroxydeca-5,9-dienoate 
• 1330680-37-9 (6Z,9R,10E,12S,13R)-13-{[tert-butyldiphenylsilyloxy]methyl}-9,12-dihydroxy-1-oxacyclotrideca-6,10-dien-2-one 
• 1330680-38-0 (3R,5Z)-((2R,3S)-1-(tert-butyldiphenylsilyloxy)-3-(4-methoxybenzyloxy)pent-4-en-2-yl)-8-(4-methoxybenzyloxy)deca-5,9-dienoate 

Relevant academic research and scientific papers

Ring-closing metathesis (RCM) based synthesis of the macrolactone core of amphidinolactone A

A convergent synthesis of the macrolactone core of amphidinolactone A has been achieved, in a 10 step linear sequence with 32% overall yield, through a ring-closing metathesis reaction as the macrolactonization step. The RCM precursor was obtained by the