954416-30-9Relevant academic research and scientific papers
Ring-closing metathesis (RCM) based synthesis of the macrolactone core of amphidinolactone A
Mohapatra, Debendra K.,Pattanayak, Manas R.,Das, Pragna P.,Pradhan, Tapas R.,Yadav
, p. 5630 - 5632 (2011/09/16)
A convergent synthesis of the macrolactone core of amphidinolactone A has been achieved, in a 10 step linear sequence with 32% overall yield, through a ring-closing metathesis reaction as the macrolactonization step. The RCM precursor was obtained by the
Total synthesis of aspinolide B: a ring-closing metathesis approach
Ghosh, Subhash,Rao, R. Vengal
, p. 6937 - 6940 (2008/02/13)
A highly convergent stereoselective total synthesis of aspinolide B, a 10-membered lactone is described. The key step includes a ring-closing metathesis reaction to construct the 10-membered ring and the E-olefinic moiety. d-Mannitol was used as a chiral
