133070-67-4

Basic information

• Product Name: 4-nitro-benzoic acid-[((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]; N-(4-nitro-benzoyl)-(+)-pseudoephedrine
• CAS NO: 133070-67-4
• Molecular Weight: 314.341
• Mol File: 133070-67-4.mol

Chemical Properties

• CAS DataBase Reference: 4-nitro-benzoic acid-[((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]; N-(4-nitro-benzoyl)-(+)-pseudoephedrine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitro-benzoic acid-[((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]; N-(4-nitro-benzoyl)-(+)-pseudoephedrine(133070-67-4)
• EPA Substance Registry System: 4-nitro-benzoic acid-[((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide]; N-(4-nitro-benzoyl)-(+)-pseudoephedrine(133070-67-4)

Safety Data

• Hazardous Substances Data: 133070-67-4(Hazardous Substances Data)

Upstream product

• 90-82-4 pseudoephedrine 
• 122-04-3 4-nitro-benzoyl chloride 
• 133160-98-2 4-nitro-benzoic acid-[((1S,2R)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide] 
• 1184662-59-6 3-(4-nitrophenyl)-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-one 

Downstream Products

• 321-97-1 (1R,2R)-pseudoephedrine 

Relevant articles and documents

Reaction of α,β-alkynylketones with β-amino alcohols: Pseudoephedrine- assisted cleavage of triple bond via formal internal redox process

Reaction of 3-aryl-1-(3,4,5-trimethoxyphenyl)prop-2-yn-1-ones with (+)-pseudoephedrine leads to products of alkyne moiety cleavage, namely, 1-(3,4,5-trimethoxyphenyl)ethanone and N-(1-hydroxy-1-phenylprop-2-yl)-N-methylbenzamides. In the course of the process one of alkyne carbons undergoes a formal reduction to a Me group, whereas the other one is oxidized to a C(O)NRR' moiety.