133098-05-2Relevant articles and documents
The fluoromethyl ether sevoflurane as a fluoride source in halogen-exchange reactions 1
Rozov, Leonid A.,Lessor, Ralph A.,Kudzma, Linas V.,Ramig, Keith
, p. 51 - 54 (1998)
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether (sevoflurane), fluoromethyl 1,1,2,3,3,3-hexafluoropropyl ether, and fluoromethyl 1,2,2,2-tetrafluoroethyl ether are found to be selective fluoride donors in some halogen-exchange reactions. For example, treatment of a mixture of a polychlorinated substrate and one equivalent of sevoflurane with a catalytic amount of antimony pentachloride gives a monofluorinated product and one equivalent of chloromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether as by-product.
General anesthetics. 3. Fluorinated methyl ethyl ethers as anesthetic agents.
Terrell,Speers,Szur,Ucciardi,Vitcha
, p. 604 - 606 (1972)
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METHOD FOR PRODUCING HALOGENATED ETHER
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Paragraph 0109-0111, (2020/03/05)
PROBLEM TO BE SOLVED: To provide a method for producing 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether (isoflurane) or 1,2,2,2-tetrafluoroethyl difluoromethyl ether (desflurane) useful as an inhaled anesthetic, on an industrial scale with high efficie
Improvements in or relating to contrast agents
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, (2008/06/13)
Combined preparations comprising an injectable gas dispersion and a coadministrable diffusible component which is capable of inward diffusion into the dispersed gas so as to promote temporary growth of the gas in vivo, the preparations being for use as contrast agents in ultrasound cardiac studies of patients who have undergone physical exercise-induced stress in order to promote vasodilatation.