133101-55-0

Upstream product

• 1655-03-4 1-cyclohex-1-enyl-propan-1-one 
• 133101-44-7 γ-(1-cyclohexen-1-yl)-β-methyl-γ-oxobutanoic acid 
• 108-94-1 cyclohexanone 
• 5330-61-0 1-nitromethyl-cyclohexene 
• 1351662-96-8 C₁₂H₁₉NO₄ 

Relevant academic research and scientific papers

A flexible approach to hexahydronaphthalene-1-carboxylates

A flexible approach to hexahydronaphthalene-1-carboxylates based on the Favorskii rearrangement of 1,1-dichloro bicyclo[5.4.0]undec-5-en-2-ones has been devised. 1,1-Dichloro bicyclo[5.4.0]undec-5-en-2-ones can be prepared from readily available cyclohexa

Stereoselective Reduction of γ-Oxobutanoic Acids Using DIBAL-H and ZnCl2

A variety of γ-aromatic γ-ketobutanoic acids can be reduced selectively, under optimized conditions, by the use of DIBAL-H and ZnCl2 to provide the (RS,SR)-γ-aryl-γ-hydroxy-β-methylbutanoic acids.Further evidence has been gathered to support the hypothesis that the reaction proceeds by formation of a seven-membered ring complex with the aluminium or zinc atom bridging the ketone and carboxyl groups which preceeds the reduction step and that this templated reduction accounts for observed high diastereoselectivity.Also we have shown that some γ-aryl-γ-butyrolactones can be easily transformed via an oxidative cleavage of the aromatic ring to provide selective synthesis of either cis- or trans-tetrahydro-3-methyl-5-oxo-2-furancarboxylic acid derivatives.