5330-61-0

Basic information

• Product Name: 1-(NITROMETHYL)CYCLOHEX-1-ENE
• Synonyms: 1-(NITROMETHYL)CYCLOHEX-1-ENE;1-(Nitromethyl)cyclohexene
• CAS NO: 5330-61-0
• Molecular Formula: C₇H₁₁NO₂
• Molecular Weight: 141.17
• Mol File: 5330-61-0.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 109 °C
• Flash Point: 78.5 °C
• Appearance: /
• Density: 1.072 g/cm³
• Vapor Pressure: 0.242mmHg at 25°C
• Refractive Index: 1.489
• PKA: 9.27±0.20(Predicted)
• CAS DataBase Reference: 1-(NITROMETHYL)CYCLOHEX-1-ENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(NITROMETHYL)CYCLOHEX-1-ENE(5330-61-0)
• EPA Substance Registry System: 1-(NITROMETHYL)CYCLOHEX-1-ENE(5330-61-0)

Safety Data

• Hazardous Substances Data: 5330-61-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 73, p. 2359, 1951 DOI: /10.1021/ja01149a511

InChI:InChI=1/C7H11NO2/c9-8(10)6-7-4-2-1-3-5-7/h4H,1-3,5-6H2

Upstream product

• 75-52-5 nitromethane 
• 108-94-1 cyclohexanone 
• 27861-39-8 (nitromethylene)cyclohexane 
• 3164-74-7 1-(nitromethyl)cyclohexyl acetate 
• 670-80-4 4-cyclohexen-1-ylmorpholine 
• 625-75-2 nitroacetic acid 
• 3164-73-6 1-nitromethylcyclohexanol 

Downstream Products

• 99063-44-2 2-cyclohex-1-enyl-2-nitro-propane-1,3-diol 
• 854724-08-6 3-benzyloxy-1-cyclohex-1-enyl-1-nitro-propan-2-ol 
• 3309-27-1 N,N-dicyclohexylmethylamine 
• 98430-89-8 (+/-)-1r,2t-dibromo-1-nitromethyl-cyclohexane 
• 1855-63-6 cyclohex-1-enecarbonitrile 
• 96914-60-2 dimethyl 2-(cyclohex-1-en-1-yl)cyclopropane-1,1-dicarboxylate 
• 408353-23-1 N,N'-(1-cyclohex-1-enyl-2-methyl-ethanediyl)-bis-acetamide 
• 408353-18-4 N-(2-cyclohex-1-enyl-1-methyl-2-nitro-ethyl)-acetamide 
• 854910-00-2 acetic acid-(2-cyclohex-1-enyl-1-methyl-2-nitro-ethyl ester) 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

Regioselective intramolecular Markovnikov and anti-Markovnikov hydrofunctionalization of alkenes: Via photoredox catalysis

Highly regioselective Markovnikov hydrofunctionalization of alkenes was successfully realized via photoredox catalysis by introducing a urea group and fine tuning the hydrogen atom transfer catalysts. The anti-Markovnikov hydroamination of alkenes was also achieved with high yields and stereoselectivities in this work.

Continuous-flow synthesis using a column reactor packed with heterogeneous catalysts: A convenient production of nitroolefins by using amino-functionalized silicagel

A continuous-flow synthesis of β-nitroolefins by using heterogeneous base catalysts has been developed. Although the use of an excess amount of nitro-donor such as nitromethane is required in conventional methods, nearly equimolar amounts of nitro-donors and carbonyl compounds are sufficient for high-yielding production of nitroolefins. Catalysts for this flow protocol are inexpensive and abundant, and high durability and high productivity were also realized by using an appropriate second support.