133101-60-7

Basic information

• Product Name: cis-(RS,SR)-γ-hydroxy-γ-(2-methoxyphenyl)-β-methylbutanoic acid lactone
• CAS NO: 133101-60-7
• Molecular Weight: 206.241
• Mol File: 133101-60-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-(RS,SR)-γ-hydroxy-γ-(2-methoxyphenyl)-β-methylbutanoic acid lactone(CAS DataBase Reference)
• NIST Chemistry Reference: cis-(RS,SR)-γ-hydroxy-γ-(2-methoxyphenyl)-β-methylbutanoic acid lactone(133101-60-7)
• EPA Substance Registry System: cis-(RS,SR)-γ-hydroxy-γ-(2-methoxyphenyl)-β-methylbutanoic acid lactone(133101-60-7)

Safety Data

• Hazardous Substances Data: 133101-60-7(Hazardous Substances Data)

Upstream product

• 133101-50-5 γ-(2-methoxyphenyl)-β-methyl-γ-oxobutanoic acid 
• 135-02-4 ortho-anisaldehyde 
• 7452-01-9 1-(o-methoxyphenyl)-1-propanol 
• 5561-92-2 1-(2-methoxyphenyl)propan-1-one 

Relevant articles and documents

Stereoselective Reduction of γ-Oxobutanoic Acids Using DIBAL-H and ZnCl2

A variety of γ-aromatic γ-ketobutanoic acids can be reduced selectively, under optimized conditions, by the use of DIBAL-H and ZnCl2 to provide the (RS,SR)-γ-aryl-γ-hydroxy-β-methylbutanoic acids.Further evidence has been gathered to support the hypothesis that the reaction proceeds by formation of a seven-membered ring complex with the aluminium or zinc atom bridging the ketone and carboxyl groups which preceeds the reduction step and that this templated reduction accounts for observed high diastereoselectivity.Also we have shown that some γ-aryl-γ-butyrolactones can be easily transformed via an oxidative cleavage of the aromatic ring to provide selective synthesis of either cis- or trans-tetrahydro-3-methyl-5-oxo-2-furancarboxylic acid derivatives.