133116-39-9Relevant academic research and scientific papers
[Hydroxy(tosyloxy)iodo]benzene in organic synthesis: A facile synthesis of furo[3,2-c]coumarins using-tosyloxyketones
Prakash, Om,Wadhwa, Deepak,Hussain, Khalid,Kumar, Ravi
, p. 2947 - 2951 (2012)
Facile synthesis of furo[3,2-c]coumarins (2a-g) via cyclocondensation of 4-hydroxycoumarin and-tosyloxyketones (1a-g) is described. A plausible mechanism involving C-C bond formation followed by 5-exo-tet cyclization is suggested.
Iodine-mediated formal [3 + 2] annulation for synthesis of furocoumarin from oxime esters
Dang, Ha V.,Ha, Hiep Q.,Le, Phong Q.,Le, Tri Minh,Nguyen, Huong T. D.,Pham, Quyen T.,Truong, Thanh
, p. 44332 - 44338 (2020/12/25)
A novel synthesis of furocoumarins was developed by a reaction between oxime esters and 4-hydroxycoumarins. The reaction was proposed to undergo radical mechanism mediated by iodine, a cheap and common laboratory reagent. Mechanistic studies showed the ke
Metal-Free Synthesis of Furocoumarins: An Approach via Iodine-Promoted One-Pot Cyclization between 4-Hydroxycoumarins and Acetophenones
Pham, Phuc H.,Nguyen, Que T. D.,Tran, Nhu K. Q.,Nguyen, Vu H. H.,Doan, Son. H.,Ha, Hiep Q.,Truong, Thanh,Phan, Nam T. S.
supporting information, p. 4431 - 4435 (2018/09/11)
A transition metal-free approach was developed to achieve substituted furocoumarins via an iodine-promoted one-pot cyclization between 4-hydroxycoumarins and acetophenones. High yields of furocoumarins were achieved in the presence of NH4OAc as
A new route to substituted furocoumarins via copper-catalyzed cyclization between 4-hydroxycoumarins and ketoximes
To, Tuong A.,Vo, Yen H.,Nguyen, Anh T.,Phan, Anh N. Q.,Truong, Thanh,Phan, Nam T. S.
supporting information, p. 5086 - 5089 (2018/07/29)
A new route to substituted furocoumarins via copper-catalyzed cyclization between 4-hydroxycoumarins and ketoximes was developed. CuBr2 exhibited higher activity than other copper salts, affording the desired furocoumarins in high yields. The transformation proceeded readily in the absence of stoichiometric external oxidants. The significance of this synthetic strategy would be (1) the easily available starting materials; (2) low cost catalyst CuBr2; and (3) being without stoichiometric external oxidants. This protocol is complementary to previous approaches in the synthesis of substituted furocoumarins.
(2-CHLORO-2-NITROETHENYL)BENZENES AS SYNTHONS: A GENERAL METHOD FOR THE PREPARATION OF 2,3-DIHYDRO-2-NITRO-3-PHENYL-4H-FUROBENZOPYRAN-4-ONES AND 3-PHENYL-4H-FUROBENZOPYRAN-4-ONES
Dauzonne, Daniel,Josien, Hubert,Demerseman, Pierre
, p. 7359 - 7371 (2007/10/02)
We describe a convenient and general method for the preparation of 2,3-dihydro-2-nitro-3-phenyl-4H-furobenzopyran-4-ones from 4-hydroxycoumarin and (2-chloro-2-nitroethenyl)benzenes in the presence of potassium fluoride.Using the same starting materials and by replacing potassium fluoride with triethylamine the hitherto unknown 3-phenyl-4H-furobenzopyran-4-ones are obtained in a one-pot procedure.
