133124-10-4

Upstream product

• 98674-86-3 (S)-(-)-4-(2-chlorophenyl)-5,5-dimethyl-2-hydroxy-1,3,2-dioxaphosphorinane-2-oxide 
• 133164-40-6 (R)-(+)-1-(2'-chlorophenyl)-2,2-dimethyl-1,3-propanediol 
• 78-84-2 isobutyraldehyde 

Relevant academic research and scientific papers

1-Aryl-2,2-dimethyl-1,3-propanediols as chiral auxiliares. Acetal formation with α,β-unsaturated aldehydes and analysis of the stereochemistry of cyclopropanation

Optically pure 1-aryl- (phenyl and 2-chlorophenyl) 1,3-propanediols, 1a and 1b, condense smoothly with aldehydes to provide the corresponding cyclic acetals 3.Except in cases that the aldehyde is substituted at the α-carbon atom, a single product is obtai