13313-18-3Relevant articles and documents
Colorimetric 'naked-eye' sensor for anions based on conformational flexible tripodal receptor
Bao, Shuang,Gong, Wei-Tao,Chen, Wen-Dan,Ye, Jun-Wei,Lin, Yuan,Ning, Gui-Ling
, p. 115 - 119 (2011)
A new tripodal receptor for anion sensing based on amide-pyridinium as recognition site and nitro-benzene as signaling unit was designed and successfully synthesized. This receptor showed high selectivity and strong binding affinity toward AcO-
N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2)
Zimmer, Christina,Hafner, Marieke,Zender, Michael,Ammann, Dominic,Hartmann, Rolf W.,Vock, Carsten A.
supporting information; experimental part, p. 186 - 190 (2011/02/25)
A series of 23 N-(Pyridin-3-yl)benzamides was synthesized and evaluated for their potential to inhibit human steroid-11β-hydroxylase (CYP11B1) and human aldosterone synthase (CYP11B2). The most potent and selective CYP11B2 inhibitors (IC50 valu
Substituted cyclic amine compound, production process thereof and pharmaceutical composition for circulatory organ use containing the same
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, (2008/06/13)
A substituted cyclic amine compound represented by the following general formula (1) STR1 wherein each of R1 to R5 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or the like, A represents a carbonyl group or a sulfonyl group, B represents a methine moiety or a nitrogen atom, D represents a methine moiety, a nitrogen atom or =N(→O)-- and n is an integer of 2 to 3; and synthetic methods thereof. The inventive compound is useful in preventing and treating circulatory organ-related diseases such as hypertension, ischemic heart disease, cerebrovascular disease, peripheral circulatory disease and the like.