133145-48-9

Usage

Chemical class

Chlorophenoxy herbicides

Usage

Control of broadleaf weeds in cereal crops (e.g., wheat, barley, and oats)

Mode of action

Interferes with the growth of unwanted plants, leading to their death

Mammalian toxicity

Low toxicity

Application

Agricultural settings

Safety precautions

Handle with care and follow proper safety measures to prevent harm to humans and the environment

Upstream product

• 2181-42-2 trimethylsulphonium iodide 
• 2234-16-4 1-(2,4-dichlorophenyl)ethan-1-one 
• 1774-47-6 trimethylsulfoxonium iodide 

Downstream Products

• 158905-35-2 6-chloro-3-methyl-1H-indole 
• 1283086-25-8 C₂₃H₂₄Cl₂N₂O 

Relevant academic research and scientific papers

AZEPINO [4, 5-B] INDOLES AND METHODS OF USE

This disclosure relates to new azepino[4,5-b]indole compounds that may be used to modulate a histamine receptor in an individual. Novel compounds are described, including new 1, 2,3,4,5, 6-tetrahydroazepino[4,5-b]indoles. Pharmaceutical compositions are also provided.

PYRIDO (4,3-B) INDOLES CONTAINING RIGID MOIETIES

This disclosure is directed to pyrido[4,3-b]indoles having rigid moieties. The compounds in one embodiment are pyrido[4,3-b]indoles having an unsaturated hydrocarbon moiety. The compounds in another embodiment are pyrido[4,3-b]indoles having a cycloalkyl, cycloalkenyl or heterocyclyl moiety. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

A short synthesis of 3,6-disubstituted N-2-thienyl/aryl-indoles

A short synthetic strategy for 3,6-disubstituted-N-2-thienyl/aryl-indoles, involving reaction of substituted 2,4-difluoro/dichloro-styrene epoxide with substituted 2-formylaminothiophenes or substituted N-formylanilines in the presence of a base followed by treatment with an acid, has been developed. The method was applied for the synthesis of a number of indoles with a variety of substituents at 1, 3, and 6 positions of the indole moiety.