133155-29-0Relevant articles and documents
Ether aryl sulfonic acid esters with improved antimalarial/anticancer activities
Betts, Lynn M.,Tam, Nga Chiu,Kabir, S. M. Humayun,Langler, Richard F.,Crandall, Ian
, p. 277 - 282 (2006)
Our previous report showed that our current benchmark agent, 4-methoxyphenyl p-toluenesulibnate, is a selective antimalarial/anticancer agent. A series of related sulfones and sulfonic acid esters is now examined. 4-Allyloxyphenyl p-toluenesulfonate is a superior antimalarial/anticancer agent. 4-Methoxyphenyl 4-nitrobenzenesulfonate is a superior antimalarial agent, but shows poorer inhibition of human skin cancer cells. CSIRO 2006.