133157-31-0 Usage
Uses
Used in Parkinson's Disease Research:
1-(4-Methoxyphenyl)-1,2,5,6-tetrahydropyridine is used as a research tool for studying the mechanisms underlying Parkinson's disease. Its neurotoxic properties allow scientists to create animal models that mimic the symptoms of the disease, which aids in understanding the pathology and progression of Parkinson's.
Used in Development of Neuroprotective Drugs:
MPTP is utilized as a model compound in the development and testing of neuroprotective drugs. Due to its ability to selectively damage dopaminergic neurons, it provides a controlled environment for evaluating the potential of new drugs to protect against or mitigate the effects of neurotoxins.
Used in Pharmaceutical Research:
1-(4-Methoxyphenyl)-1,2,5,6-tetrahydropyridine is used as a starting material or intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure makes it a valuable component in the development of new drugs targeting the central nervous system.
Used in Drug Delivery Systems:
In the field of drug delivery, MPTP can be used as a model compound to study the transport and targeting of neurotoxins across the blood-brain barrier. This knowledge can be applied to develop more effective drug delivery systems for treating neurological disorders.
Used in Toxicology Studies:
MPTP is employed in toxicology studies to investigate the effects of neurotoxic substances on the brain and nervous system. Understanding the mechanisms of MPTP-induced toxicity can help in the development of strategies to counteract or prevent similar damage caused by other neurotoxic agents.
Used in Environmental Monitoring:
1-(4-Methoxyphenyl)-1,2,5,6-tetrahydropyridine can be used as a reference compound in environmental monitoring to detect and quantify the presence of neurotoxic substances in the environment, which is crucial for assessing potential health risks and implementing preventive measures.
Check Digit Verification of cas no
The CAS Registry Mumber 133157-31-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,1,5 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 133157-31:
(8*1)+(7*3)+(6*3)+(5*1)+(4*5)+(3*7)+(2*3)+(1*1)=100
100 % 10 = 0
So 133157-31-0 is a valid CAS Registry Number.
133157-31-0Relevant articles and documents
FeCl3-Catalyzed oxidative allylation of sp2 and sp3 C-H bond adjacent to a nitrogen atom: Easy access to homoallyl tertiary amines
Kumaraswamy, Gullapalli,Murthy, Akula Narayana,Pitchaiah, Arigala
supporting information; experimental part, p. 3916 - 3919 (2010/07/05)
Figure presented Oxidative allylation to sp2- and sp 3-carbon attached to the nitrogen atom was accomplished. The α-allylation of tertiary amines was catalyzed by easily available hydrated iron(III) chloride in combination with air or aqueous tBuOOH. Remarkably, N-allyl- and N-propagyl-tethered tertiary amines were also allylated through this protocol.
