133161-96-3

Usage

Uses

Used in Pharmaceutical Industry:
TETRANOR-PGDM is used as a biomarker for assessing endogenous production of PGD2, which plays a crucial role in various physiological processes. Monitoring the levels of TETRANOR-PGDM can help in understanding the underlying mechanisms of diseases and conditions related to PGD2, such as allergic reactions, asthma, and sleep disorders.
Used in Research and Development:
TETRANOR-PGDM is used as a research tool to study the metabolism and pharmacological effects of PGD2. It aids in the development of new drugs and therapies targeting the PGD2 pathway, which can be beneficial in treating various diseases and conditions.
Used in Diagnostic Applications:
TETRANOR-PGDM can be used as a diagnostic marker to identify and monitor the progression of diseases and conditions related to PGD2. Its measurement in biological samples can provide valuable insights into the patient's health status and help in making informed treatment decisions.
Used in Drug Delivery Systems:
TETRANOR-PGDM can be incorporated into drug delivery systems to improve the targeting and efficacy of drugs that modulate the PGD2 pathway. This can lead to the development of novel therapeutic approaches for treating diseases and conditions associated with PGD2 dysregulation.

Upstream product

• 118908-29-5 6-[(1R,2R,3S,5S)-3,5-Diacetoxy-2-((Z)-4-methoxycarbonyl-but-2-enyl)-cyclopentyl]-4-oxo-hexanoic acid methyl ester 
• 118908-19-3 3-{2-[2-((3aR,4R,5R,6aS)-5-Hydroxy-2-oxo-hexahydro-cyclopenta[b]furan-4-yl)-ethyl]-[1,3]dithiolan-2-yl}-propionic acid methyl ester 
• 118908-29-5 6-[(1R,2R,3S,5S)-3,5-Diacetoxy-2-((E)-4-methoxycarbonyl-but-2-enyl)-cyclopentyl]-4-oxo-hexanoic acid methyl ester 
• 118908-22-8 3-(2-{2-[(1R,2R,3S,5R)-3-Hydroxy-2-[(E)-4-(4-methyl-2,6,7-trioxa-bicyclo[2.2.2]oct-1-yl)-but-2-enyl]-5-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-ethyl}-[1,3]dithiolan-2-yl)-propionic acid methyl ester 
• 38754-71-1 (3aR,4R,5R,6aS)-4-formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl biphenyl-4-carboxylate 
• 118908-25-1 (E)-5-[(1R,2R,3R,5S)-5-Acetoxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-pent-3-enoic acid methyl ester 
• 118934-04-6 (E)-5-((1R,2R,3R,5S)-5-Acetoxy-3-methanesulfonyloxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-cyclopentyl)-pent-3-enoic acid methyl ester 
• 118908-27-3 (E)-5-((1R,2R,3S,5S)-3,5-Diacetoxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-cyclopentyl)-pent-3-enoic acid methyl ester 
• 118908-24-0 (E)-5-[(1R,2R,3R,5S)-5-Hydroxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-pent-3-enoic acid methyl ester 
• 118908-23-9 (E)-5-[(1R,2R,3R,5S)-2-{2-[2-(2-Carboxy-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-5-hydroxy-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-pent-3-enoic acid 
• 118908-26-2 (E)-5-((1R,2R,3R,5S)-5-Acetoxy-3-hydroxy-2-{2-[2-(2-methoxycarbonyl-ethyl)-[1,3]dithiolan-2-yl]-ethyl}-cyclopentyl)-pent-3-enoic acid methyl ester 
• 118908-18-2 methyl 3-<2-(2-octan-t-6-yl>ethyl)-1,3-dithiolan-2-yl>propionate 
• 118908-16-0 Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-((E)-5-methoxycarbonyl-3-oxo-pent-1-enyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 
• 118908-17-1 Biphenyl-4-carboxylic acid (3aR,4R,5R,6aS)-4-(5-methoxycarbonyl-3-oxo-pentyl)-2-oxo-hexahydro-cyclopenta[b]furan-5-yl ester 

Relevant academic research and scientific papers

SYNTHESIS OF THE MAJOR URINARY METABOLITE OF PROSTAGLANDIN D2

Starting from the Corey lactone (3), the total synhesis of a specific urinary metabolite of prostaglandin D2, viz., (Z)-9α,11β-dihydroxy-15-oxo-2,3,18,19-tetranorprost-5-ene-1,20-dioic acid (1) and its 5E-isomer is described.The synthetic mater