133166-04-8

Upstream product

• 136694-19-4 4-(quinolin-2-ylmethoxy)-phenylhydrazine 
• 75-09-2 dichloromethane 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 

Downstream Products

• 133165-99-8 4-{(4-Chloro-benzyl)-[4-(quinolin-2-ylmethoxy)-phenyl]-hydrazono}-2,2-dimethyl-pentanoic acid methyl ester 
• 133165-84-1 4-{(4-Chloro-benzyl)-[4-(quinolin-2-ylmethoxy)-phenyl]-hydrazono}-pentanoic acid ethyl ester 
• 133165-83-0 N-(4-Chloro-benzyl)-N'-[1,3-dimethyl-but-(E)-ylidene]-N-[4-(quinolin-2-ylmethoxy)-phenyl]-hydrazine 
• 133190-96-2 N-(4-Chloro-benzyl)-N'-[1-methyl-prop-(E)-ylidene]-N-[4-(quinolin-2-ylmethoxy)-phenyl]-hydrazine 
• 133166-02-6 (4-Chloro-phenyl)-[4-(quinolin-2-ylmethoxy)-phenyl]-amine 
• 133165-93-2 2-[1-(4-Chloro-benzyl)-2-ethyl-1H-indol-5-yloxymethyl]-quinoline 
• 133165-90-9 2-[1-(4-Chloro-benzyl)-2,3-dimethyl-1H-indol-5-yloxymethyl]-quinoline 
• 133165-94-3 2-[1-(4-Chloro-benzyl)-2-isobutyl-1H-indol-5-yloxymethyl]-quinoline 
• 133166-00-4 methyl 3-[N-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoate 
• 133166-01-5 2-[1-(4-Chloro-benzyl)-2-methyl-5-(quinolin-2-ylmethoxy)-1H-indol-3-yl]-2-methyl-propionic acid methyl ester 
• 136668-42-3 quiflapon 
• 136694-80-9 Methyl 3-[N-(4-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-diethylpropanoate 
• 136694-18-3 methyl 3-[3-(1,1-dimethylethylthio)-5-(quinolin-2-ylmethoxy)-1-(4-chlorophenylmethyl)indol-2-yl]-2,2-dimethylpropionate 

Relevant academic research and scientific papers

Hydrazine synthesis

An improved synthesis is described for producing a quinolinylmethoxyphenyl hydrazine which is an intermediate in the preparation of quinolinylmethoxyindoles useful as inhibitors of leukotriene biosynthesis. The improved process eliminates two isolation steps and yields a product of high purity.

(Quinolin-2-ylmethoxy)tetrahydrocarbazoles as inhibitors of the biosynthesis of leukotrienes

Compounds having the Formula I: STR1 are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, pl

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

Compounds having the formula I: STR1 are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

(Quinolin-2-ylmethoxy)indole/cyclodextrin complex

A complex of cyclodextrin and 3-[N-(p-chlorobenzyl)-3-(t-buthylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid, sodium salt is more soluble in water than the sodium salt alone. The complex is useful as an anti-asthmatic, anti-allergic

Amorphous (quinolin-2-ylmethoxy)indole compounds which have useful pharmaceutical utility

A form of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-a