133167-63-2

Upstream product

• 119244-39-2 9-[(3aR,4R,6S,6aS)-6-(4-Methoxy-phenylsulfanylmethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-ylamine 
• 133167-56-3 N-Benzoyl-N-{9-[(3aR,4R,6S,6aS)-6-(4-methoxy-benzenesulfinylmethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-yl}-benzamide 
• 133167-55-2 N-Benzoyl-N-{9-[(3aR,4R,6S,6aS)-6-(4-methoxy-phenylsulfanylmethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-yl}-benzamide 
• 133167-62-1 N-Benzoyl-N-(9-{(3aR,4R,6S,6aS)-6-[fluoro-(4-methoxy-phenylsulfanyl)-methyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 

Downstream Products

• 133191-04-5 N-Benzoyl-N-(9-{(3aR,4R,6S,6aS)-6-[chloro-fluoro-(4-methoxy-benzenesulfinyl)-methyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 

Relevant academic research and scientific papers

4',5'-Unsaturated 5'-Halogenated Nucleosides. Mechanism-Based and Competitive Inhibitors of S-Adenosyl-L-homocysteine Hydrolase

The design and synthesis of (E)- and (Z)-5'-fluoro-4',5'-didehydro-5'-deoxyadenosine (6 and 13, respectively), a new class of mechanism-based inhibitors of S-adenosyl-L-homocysteine (SAH) hydrolase, is described.A number of analogues of 6 and 13 were synt