133167-55-2

Upstream product

• 119244-39-2 9-[(3aR,4R,6S,6aS)-6-(4-Methoxy-phenylsulfanylmethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-ylamine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 133191-04-5 N-Benzoyl-N-(9-{(3aR,4R,6S,6aS)-6-[chloro-fluoro-(4-methoxy-benzenesulfinyl)-methyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 
• 133167-57-4 N⁶,N⁶-dibenzoyl-5'-deoxy-5'-chloro-5'-<(4-methoxyphenyl)sulfinyl>-2',3'-O-isopropylideneadenosine 
• 133167-63-2 N-Benzoyl-N-(9-{(3aR,4R,6S,6aS)-6-[fluoro-(4-methoxy-benzenesulfinyl)-methyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 
• 133167-62-1 N-Benzoyl-N-(9-{(3aR,4R,6S,6aS)-6-[fluoro-(4-methoxy-phenylsulfanyl)-methyl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 
• 133167-64-3 (E)-N⁶-benzoyl-4',5'-didehydro-5'-chloro-5'-fluoro-2',3'-O-isopropylideneadenosine 
• 133167-65-4 N-(9-{(2R,3R,4S)-5-[1-Chloro-1-fluoro-meth-(E)-ylidene]-3,4-dihydroxy-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide 
• 133167-60-9 N-(9-{(2R,3R,4S)-5-[1-Chloro-meth-(Z)-ylidene]-3,4-dihydroxy-tetrahydro-furan-2-yl}-9H-purin-6-yl)-benzamide 
• 133167-58-5 N-(9-{(3aR,4R,6aS)-6-[1-Chloro-meth-(Z)-ylidene]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-9H-purin-6-yl)-benzamide 
• 133167-56-3 N-Benzoyl-N-{9-[(3aR,4R,6S,6aS)-6-(4-methoxy-benzenesulfinylmethyl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-9H-purin-6-yl}-benzamide 

Relevant academic research and scientific papers

4',5'-Unsaturated 5'-Halogenated Nucleosides. Mechanism-Based and Competitive Inhibitors of S-Adenosyl-L-homocysteine Hydrolase

The design and synthesis of (E)- and (Z)-5'-fluoro-4',5'-didehydro-5'-deoxyadenosine (6 and 13, respectively), a new class of mechanism-based inhibitors of S-adenosyl-L-homocysteine (SAH) hydrolase, is described.A number of analogues of 6 and 13 were synt