1331741-89-9Relevant academic research and scientific papers
Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors
Pastor, Joaquín,Oyarzabal, Julen,Saluste, Gustavo,Alvarez, Rosa María,Rivero, Virginia,Ramos, Francisco,Cendón, Elena,Blanco-Aparicio, Carmen,Ajenjo, Nuria,Cebriá, Antonio,Albarrán,Cebrián, David,Corrionero, Ana,Fominaya, Jesús,Montoya, Guillermo,Mazzorana, Marco
, p. 1591 - 1597 (2012/04/10)
PIM kinases have become targets of interest due to their association with biochemical mechanisms affecting survival, proliferation and cytokine production. 1,2,3-Triazolo[4,5-b]pyridines were identified as PIM inhibitors applying a scaffold hopping approa
TRIAZOLO [4, 5 - B] PYRIDIN DERIVATIVES
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Page/Page column 92, (2011/09/19)
There is provided compounds of formula (I), wherein R1, R2, R3 and R4 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful
