6604-76-8Relevant academic research and scientific papers
IMIDAZOPYRIDINE DERIVATIVES AS PI3K INHIBITORS
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Page/Page column 119, (2012/11/13)
New imidazopyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Phosphoinositide 3-Kinases (PI3Ks).
Hit to lead evaluation of 1,2,3-triazolo[4,5-b]pyridines as PIM kinase inhibitors
Pastor, Joaquín,Oyarzabal, Julen,Saluste, Gustavo,Alvarez, Rosa María,Rivero, Virginia,Ramos, Francisco,Cendón, Elena,Blanco-Aparicio, Carmen,Ajenjo, Nuria,Cebriá, Antonio,Albarrán,Cebrián, David,Corrionero, Ana,Fominaya, Jesús,Montoya, Guillermo,Mazzorana, Marco
scheme or table, p. 1591 - 1597 (2012/04/10)
PIM kinases have become targets of interest due to their association with biochemical mechanisms affecting survival, proliferation and cytokine production. 1,2,3-Triazolo[4,5-b]pyridines were identified as PIM inhibitors applying a scaffold hopping approa
Compounds with antiulcer and antisecretory activity. III. N-substituted imidazolones condensed with nitrogen-containing heteroaromatic rings
Bianchi,Butti,Rossi,et al.
, p. 501 - 506 (2007/10/02)
The syntheses of imidazo[4,5-b]pyridin-2-ones and -thiones, imidazo [4,5-c]pyridin-2-ones and 7,9-dihydro-8H-purin-8-ones arylated (or heteroarylated) at an imidazolone nitrogen are reported. Only some compounds of the first series have marked antisecreto
