1331778-53-0

Basic information

• Product Name: C₂₁H₂₆N₄O₄
• Synonyms: C₂₁H₂₆N₄O₄
• CAS NO: 1331778-53-0
• Molecular Weight: 398.462
• Mol File: 1331778-53-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₆N₄O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₆N₄O₄(1331778-53-0)
• EPA Substance Registry System: C₂₁H₂₆N₄O₄(1331778-53-0)

Safety Data

• Hazardous Substances Data: 1331778-53-0(Hazardous Substances Data)

Upstream product

• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 1885-14-9 phenyl chloroformate 
• 119285-07-3 4-(5-aminopyridin-2-yl)piperazine-1-carboxylic acid tert-butyl ester 
• 82205-58-1 1-(5-nitro-2-pyridinyl)piperazine 
• 193902-78-2 tert-butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate 
• 4548-45-2 2-chloro-5-nitropyridine 

Relevant articles and documents

Design and synthesis of novel antifungal triazole derivatives with good activity and water solubility

In order to find novel antifungal agents with good activity and aqueous solubility, a series of SYN-2869 analogues containing a pyridine ring were synthesized and evaluated for their in vitro antifungal activity and water solubility. The results indicated that some compounds showed potent activity against six pathogenic fungi. In particular, the analogue 17a having an isobutyl substitution on the triazolone exhibited significant broad spectrum antifungal activity. In addition, the water solubility of compound 17a was sufficiently improved over SYN-2869.