1331868-52-0

Basic information

• Product Name: 2-((1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)propanamide
• CAS NO: 1331868-52-0
• Molecular Weight: 424.547
• Mol File: 1331868-52-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)propanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)propanamide(1331868-52-0)
• EPA Substance Registry System: 2-((1-(4-methoxyphenyl)-1H-benzo[d]imidazol-2-yl)thio)-N-(4-methylthiazol-2-yl)propanamide(1331868-52-0)

Safety Data

• Hazardous Substances Data: 1331868-52-0(Hazardous Substances Data)

Upstream product

• 1493-27-2 ortho-nitrofluorobenzene 
• 104-94-9 4-methoxy-aniline 
• 25914-22-1 N-(4-methoxyphenyl)benzene-1,2-diamine 
• 54381-13-4 2-nitro-4'-methoxydiphenylamine 
• 879609-86-6 C₇H₉BrN₂OS 
• 26495-07-8 1-(4-methoxyphenyl)-2,3-dihydro-1H-1,3-benzodiazole-2-thione 

Relevant articles and documents

Host-directed inhibitors of myxoviruses: Synthesis and in vitro biochemical evaluation

Drugs targeted to viral proteins are highly vulnerable to the development of viral resistance. One little explored approach to the treatment of viral diseases is the development of agents that target host factors required for virus replication. Myxoviruses are predominantly associated with acute disease and, thus, ideally suited for this approach since the necessary treatment time is anticipated to be limited. High-throughput screening previously identified benzimidazole 22407448 with broad antiviral activity against different influenza virus and paramyxovirus strains. Hit to lead chemistry has generated 6p (JMN3-003) with potent antiviral activity against a panel of myxovirus family members exhibiting EC50 values in the low nanomolar range.