1331871-18-1

Basic information

• Product Name: C₂₀H₂₅N₃O₅
• Synonyms: C₂₀H₂₅N₃O₅
• CAS NO: 1331871-18-1
• Molecular Weight: 387.436
• Mol File: 1331871-18-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₅N₃O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₅N₃O₅(1331871-18-1)
• EPA Substance Registry System: C₂₀H₂₅N₃O₅(1331871-18-1)

Safety Data

• Hazardous Substances Data: 1331871-18-1(Hazardous Substances Data)

Upstream product

• 1331871-16-9 (S)-methyl 1-((S)-2-(((benzyloxy)carbonyl)amino)-4-(2-((tert-butoxycarbonyl)amino)phenyl)-4-oxobutanoyl)pyrrolidine-2-carboxylate 
• 117269-80-4 (S)-4-[2-(2-tert-Butoxycarbonylamino-phenyl)-2-oxo-ethyl]-5-oxo-oxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 1331871-20-5 N-(2-(2-((3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl)acetyl)phenyl)-4-methylpent-3-enamide 

Relevant articles and documents

Total synthesis of tryprostatins A and B

Three distinct synthetic routes to the 2-prenyl tryptophan core skeleton of tryprostatins and their total syntheses are described. The strategies include a traditional gramine-mediated coupling reaction, Fuerstner indole synthesis, and our radical-mediated indole synthesis from o-alkenylphenyl isocyanide. The establishment of reliable conditions for the radical-mediated construction of indoles via a low-temperature radical initiator V-70 (2,2′-azobis(4- methoxy-2,4-dimethylvaleronitrile)) led to the highly efficient syntheses of tryprostatins A and B.