133188-89-3Relevant academic research and scientific papers
Preparation of Functionalized Zinc and Copper Organometallics Containing Sulfur Functionalities at the Alpha or Gamma Position
Rao, Sidduri Achyutha,Tucker, Charles E.,Knochel, Paul
, p. 7575 - 7578 (1990)
α-Chloroalkyl phenyl sulfides 1 readily insert zinc in THF at 25 deg C (0.5-2 h), affording sulfur stabilized organozinc derivatives of type 2.The presence of a functional group such as an ester or a cyano group is tolerated in these organometallics.After a transmetallation to the corresponding copper reagent 3, they react with a wide range of electrophiles.Zinc and copper organometallics bearing a thiophenyl or a phenylsulfinyl group at the γ-position have also been prepared showing the generality of our approach.
Preparation and reactivity of polyfunctional zinc and copper organometallics bearing sulfur functionalities
Achyutha Rao,Chou, Tso-Sheng,Schipor, Ioana,Knochel, Paul
, p. 2025 - 2043 (2007/10/02)
Iodomethylthiobenzoate 5 and α-chloroalkyl phenyl sulfides 6 were found to insert zinc dust in THF under very mild conditions (10-25°C, 0.5-2 h) leading to zinc α-thioorganometallics. After a transmetallation with CuCN·2 LiCl, the corresponding copper rea
