1332355-99-3Relevant academic research and scientific papers
Design, synthesis and in vitro biochemical activity of novel amino acid sulfonohydrazide inhibitors of MurC
Frlan, Rok,Kovas, Andreja,Blanot, Didier,Gobec, Stanislav,Pecar, Slavko,Obreza, Ales
experimental part, p. 295 - 310 (2012/04/23)
Mur ligases are essential enzymes involved in the cytoplasmic steps of peptidoglycan synthesis which remain attractive, yet unexploited targets. In order to develop new antibacterial agents, we have designed a series of new MurC and MurD inhibitors bearin
