133239-56-2

Upstream product

• 50773-56-3 3-benzyloxy-4-hydroxybenzaldehyde 
• 584-08-7 potassium carbonate 
• 106-94-5 propyl bromide 
• 133239-55-1 3-(methylthio)-4-hydroxy-5-(benzyloxy)benzaldehyde 
• 4815-96-7 3-bromo-4-hydroxy-5-benzyloxybenzaldehyde 

Downstream Products

• 134169-11-2 1-<3-(methylthio)-4-n-propoxy-5-(benzyloxy)phenyl>-4-(3,4,5-trimethoxyphenyl)butane-1,4-dione 
• 134236-00-3 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-hydroxyphenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134169-13-4 (-)-(1S)-1-hydroxy-1-<3-(methylsulfonyl)-4-n-propoxy-5-(benzyloxy)phenyl>-4-(3,4,5-trimethoxyphenyl)butan-4-one 
• 134169-12-3 1-<3-(methylsulfonyl)-4-n-propoxy-5-(benzyloxy)phenyl>-4-(3,4,5-trimethoxyphenyl)butane-1,4-dione 
• 140705-10-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 143395-24-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-(3-bromopropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134235-99-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-(benzyloxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134237-19-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(1-imidazoyl)-n-propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134186-92-8 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(1-morpholino)-n-propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134236-08-1 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<3-(phosphonooxy)propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 134169-24-7 (-)-trans-(2S,5S)-2-<3-<(2-oxopropyl)sulfonyl>-4-n-propoxy-5-<<<3-(dibenzyloxy)phosphoryl>oxy>propoxy>phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran 
• 143395-27-1 (R)-Methoxy-phenyl-acetic acid (S)-2-{3-benzyloxy-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzenesulfonyl}-1-methyl-ethyl ester 
• 143346-10-5 (R)-Methoxy-phenyl-acetic acid (R)-2-{3-benzyloxy-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzenesulfonyl}-1-methyl-ethyl ester 
• 134236-04-7 3-((S)-2-Hydroxy-propane-1-sulfonyl)-2-propoxy-5-[(2S,5S)-5-(3,4,5-trimethoxy-phenyl)-tetrahydro-furan-2-yl]-phenol 

Relevant academic research and scientific papers

Development, Synthesis, and Biological Evaluation of (-)-trans-(2S,5S)-2--4-n-propoxy-5-(3-hydroxypropoxy)-phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran, a Potent Orally Active Platelet-Activating Factor (PAF) Antagonist and

(-)-trans-(2S,5S)-2--4-n-propoxy-5-(3-hydroxypropoxy)phenyl>-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (10) is one of the most potent platelet-activating factor (PAF) antagonists in vitro and in vivo developed to date.This diaryl

2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein Ar is a pyridyl, dimethoxy-pyridyl or a dimethoxy-pyrazinyl group, R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing gro

2,5-DIARYL TETRAHYDROFURANS AND ANALOGS THEREOF AS PAF ANTAGONISTS

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein R 4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group and at least one of the substituents at positions 3,4 or 5 contains a hete

2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists

The present invention is directed to a specifically substituted tetrahydrofuran of the formula (I) STR1 wherein R4 is an alkylthio, alkylsulfinyl or alkylsulfonyl containing group, Y is an alkyl or substituted alkyl group, R6 is an alkyl or a substituted alkyl group and the substituents at positions 3, 4 or 5 are acyclic.