133258-40-9

Basic information

• Product Name: Pyrazine, [5-(4-fluorophenyl)-3-(1-methylethyl)-1H-pyrazol-1-yl]-
• CAS NO: 133258-40-9
• Molecular Formula: C16H15FN4
• Molecular Weight: 282.32
• Mol File: 133258-40-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Pyrazine, [5-(4-fluorophenyl)-3-(1-methylethyl)-1H-pyrazol-1-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, [5-(4-fluorophenyl)-3-(1-methylethyl)-1H-pyrazol-1-yl]-(133258-40-9)
• EPA Substance Registry System: Pyrazine, [5-(4-fluorophenyl)-3-(1-methylethyl)-1H-pyrazol-1-yl]-(133258-40-9)

Safety Data

• Hazardous Substances Data: 133258-40-9(Hazardous Substances Data)

Upstream product

• 114433-94-2 1-(4-Fluorophenyl)-3-isopropylpropan-1,3-dione 
• 54608-52-5 2-hydrazinylpyrazine 

Downstream Products

• 133258-41-0 2-[4-bromo-5-(4-Fluorophenyl)-3-(1-methylethyl)-1H-pyrazol-1-yl]pyrazine 
• 786611-53-8 (E)-(3R,5S)-7-[5-(4-Fluoro-phenyl)-3-isopropyl-1-pyrazin-2-yl-1H-pyrazol-4-yl]-3,5-dihydroxy-hept-6-enoic acid 
• 133258-45-4 trans-7-[5-(4-Fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl]-5-hydroxy-3-oxo-6-heptenoic acid, ethyl ester 
• 133258-42-1 (E)-3-[5-(4-Fluoro-phenyl)-3-isopropyl-1-pyrazin-2-yl-1H-pyrazol-4-yl]-acrylic acid ethyl ester 
• 133258-43-2 trans-3-[5-(4-Fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl]2-propen-1-ol 
• 133258-44-3 trans-3-[5-(4-Fluorophenyl)-3-(1-methylethyl)-1-(2-pyrazinyl)-1H-pyrazol-4-yl]-2-propenal 

Relevant articles and documents

Inhibitors of cholesterol biosynthesis. 6. trans-6-[2-(2-N-heteroaryl-3,5- disubstituted-pyrazol-4-yl)ethyl/ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-ones

A series of N-heteroaryl-substituted mevalonolactones were prepared and evaluated for their ability to inhibit the enzyme HMG-CoA reductase both in vitro and in vivo, and to lower plasma cholesterol in a hypercholesterolemic dog model. The goal of the str