1332634-95-3

Upstream product

• 68817-71-0 2-(4-chloroanilino)aniline 
• 327-92-4 1,5-difluoro-2,4-dinitrobenzene 
• 1332634-93-1 5-(4-chlorophenyl)-3-imino-3,5-dihydrophenazin-2-amine 
• 1332634-92-0 N-(5-amino-2,4-dinitrophenyl)-N'-(4-chlorophenyl)benzene-1,2-diamine 
• 1332634-91-9 N¹-(4-chlorophenyl)-N²-(5-fluoro-2,4-dinitrophenyl)benzene-1,2-diamine 
• 1332634-94-2 5-(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydrophenazin-2-amine 
• 4595-60-2 2-bromopyrimidine 

Relevant academic research and scientific papers

RIMINOPHENAZINES WITH 2-(HETEROARYL)AMINO SUBSTITUENTS AND THEIR ANTI-MICROBIAL ACTIVITY

The present invention relates to riminophenazines having heteroaromatic substitutions, including those with 2-heteroaryl-amino substituents, to their preparation, and to their use as drugs for treating Mycobacterium tuberculosis and other microbial infections, either alone or in combination with other anti-infective treatments.

Synthesis of new riminophenazines with pyrimidine and pyrazine substitution at the 2-N position

New riminophenazines with pyrimidine and pyrazine substituents at the 2-position were successfully synthesized. The key step is the 2-N-arylation of riminophenazines with pyrimidine and pyrazine. The optimized reaction conditions involve the use of a Pds