1332645-64-3Relevant academic research and scientific papers
N-heterocyclic carbene/Lewis acid strategy for the stereoselective synthesis of spirocyclic oxindole-dihydropyranones
Xiao, Zhaoxin,Yu, Chenxia,Li, Tuanjie,Wang, Xiang-Shan,Yao, Changsheng
supporting information, p. 3632 - 3635 (2014/08/05)
Under the cooperative catalysis of NHC/Lewis acid, the mild, straightforward [4 + 2] annulation of α-bromo-α,β-unsaturated aldehydes bearing γ-H with isatin derivatives gave spirocyclic oxindole-dihydropyranones stereoselectively. This approach is particu
N-heterocyclic carbene-catalyzed cyclization of unsaturated acyl chlorides and ketones
Shen, Li-Tao,Shao, Pan-Lin,Ye, Song
, p. 1943 - 1948 (2011/10/13)
A straightforward synthesis of optically active trifluoromethyl dihydropyranones and spirocyclic oxindole-dihydropyranones has been realized by the chiral N-heterocyclic carbenes-catalyzed cyclization of α,β- unsaturated β-methylacyl chlorides with activated trifluoromethyl ketones or isatin derivatives. Copyright
