1332698-99-3Relevant academic research and scientific papers
Ethyl malonate amides: A diketo acid offspring fragment for HIV integrase inhibition
Serafin, Katarzyna,Mazur, Pawel,Bak, Andrzej,Laine, Elodie,Tchertanov, Luba,Mouscadet, Jean-Franois,Polanski, Jaroslaw
, p. 5000 - 5005 (2011)
While searching for new HIV integrase inhibitors we discovered that some ethyl malonate amides (EMA) are active against this enzyme. Surprisingly, the main function can only very rarely be found among the reported drug candidates. We synthesised a series
