13327-27-0

Basic information

• Product Name: 6-Methylpyridazin-3(2H)-one
• Synonyms: 6-Methyl-2,3-dihydropyridazine-3-one;3-pyridazinol, 6-methyl-;3-methyl-1H-pyridazin-6-one;6-Methyl-2H-pyridazin-3-o...;3-Hydroxy-6-methylpyridazine;6-Methylpyridazine-3[2H]-one;6-Methyl-1,2-dihydropyriMidin-2-one;6-Methyl-3-pyridazinone
• CAS NO: 13327-27-0
• Molecular Formula: C₅H₆N₂O
• Molecular Weight: 110.11
• EINECS: 236-367-0
• Mol File: 13327-27-0.mol
• Article Data: 18

Chemical Properties

• Melting Point: 143-145°C
• Boiling Point: 310.3 °C at 760 mmHg
• Flash Point: 141.5 °C
• Appearance: colorless crystals
• Density: 1.22 g/cm³
• Vapor Pressure: 0.000331mmHg at 25°C
• Refractive Index: 1.576
• Storage Temp.: Room temperature.
• PKA: 11.51±0.40(Predicted)
• BRN: 109928
• CAS DataBase Reference: 6-Methylpyridazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methylpyridazin-3(2H)-one(13327-27-0)
• EPA Substance Registry System: 6-Methylpyridazin-3(2H)-one(13327-27-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 22-24/25-37-26
• HazardClass: IRRITANT
• Hazardous Substances Data: 13327-27-0(Hazardous Substances Data)

Usage

Uses

6-?Methyl-?3-?pyridazinone is a lignin-based dye used on wool. 6-?Methyl-?3-?pyridazinone is also used as a reactant for the synthesis of C-?(1-?aryl-?cyclohexyl)?-?methylamine derivatives as selective, orally available inhibitors of dipeptidyl peptidase IV, imidazopyridazinone derivatives as PDE7 inhibitors and pyridazinone derivatives with an arylpiperazinylalkyl chain as a potentent, orally active, antinociceptive agent.

Synthesis Reference(s)

Synthesis, p. 1158, 1994 DOI: 10.1055/s-1994-25663

InChI:InChI=1/C5H6N2O/c1-4-2-3-5(8)7-6-4/h2-3H,1H3,(H,7,8)

Upstream product

• 123-76-2 levulinic acid 
• 1173165-23-5 N'-acryloyl-N-(but-3-en-2-yl)-4-methylbenzenesulfonohydrazide 
• 539-88-8 4-oxopentanoic acid ethyl ester 
• 14923-67-2 4-semicarbazono-valeric acid ethyl ester 
• 99903-59-0 6-methyl-3-oxo-2,3-dihydro-pyridazine-4-carbonitrile 
• 87823-46-9 3-methyl-4,5-dihydroisoxazole-5-carboxylic acid ethyl ester 
• 89941-79-7 ethyl 2-hydroxy-4-oxovalerate 
• 1632-76-4 3-methylpyridazine 
• 873-67-6 benzonitrile oxide 
• 83297-16-9 2-t-butyl-2,3-dihydro-6-methyl-3-oxopyridazine-4-carboxylic acid 
• 21012-44-2 4-hydroxy-6-methyl-4,5-dihydro-2H-pyridazin-3-one 
• 74557-73-6 6-methyl-3-oxo-2,3-dihydro-pyridazine-4-carboxylic acid 
• 1121-79-5 3-chloro-6-methylpyridazine 
• 5157-08-4 3-methyl-4,5-dihydro-6-oxopyridazine 

Downstream Products

• 101112-87-2 (3-methyl-6-oxo-6H-pyridazin-1-yl)-phenyl-acetic acid ethyl ester 
• 6958-53-8 2-benzyl-6-methyl-2,3-dihydropyridazin-3-one 
• 37972-69-3 6-oxo-1,6-dihydropyridazine-3-carboxylic acid 
• 134142-26-0 3,7-dimethyl-3-phenyl-3H-pyrazolo<3.4-d>pyridazin-4(5H)-one 
• 120129-91-1 4-iodo-2-isopropyl-1-methoxybenzene 
• 120129-92-2 2-(3-isopropyl-4-methoxyphenyl)-6-methylpyridazin-3(2H)-one 
• 63900-47-0 6-methyl-2-phenacylpyridazin-3(2H)-one 
• 37972-69-3 6-hydroxy-pyridazine-3-carboxylic acid 
• 1404065-54-8 C₂₄H₂₈N₄O₄ 
• 1404065-49-1 C₂₁H₂₆N₆O₃ 
• 1404065-50-4 C₂₁H₂₂N₆O₄ 
• 1404065-51-5 C₂₂H₂₅N₅O₃ 
• 1404065-52-6 C₂₂H₂₇N₅O₃ 
• 1404065-53-7 C₂₃H₂₇N₅O₃ 

Relevant articles and documents

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