1332709-28-0

Basic information

• Product Name: 2-chloro-N,2-diphenyl-N-(1-phenylethyl)acetamide
• Synonyms: 2-chloro-N,2-diphenyl-N-(1-phenylethyl)acetamide
• CAS NO: 1332709-28-0
• Molecular Weight: 349.86
• Mol File: 1332709-28-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-N,2-diphenyl-N-(1-phenylethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-N,2-diphenyl-N-(1-phenylethyl)acetamide(1332709-28-0)
• EPA Substance Registry System: 2-chloro-N,2-diphenyl-N-(1-phenylethyl)acetamide(1332709-28-0)

Safety Data

• Hazardous Substances Data: 1332709-28-0(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 62-53-3 aniline 
• 1749-19-5 N-(1-phenylethylidene)aniline 
• 779-54-4 phenyl(1-phenylethyl)amine 
• 2912-62-1 α-chlorophenylacetyl chloride 

Downstream Products

• 1332709-30-4 3-phenyl-1-(1-phenylethyl)indolin-2-one 

Relevant articles and documents

Carbon-carbon bond-forming reactions of α-carbonyl carbocations: Exploration of a reversed-polarity equivalent of enolate chemistry

Carbon-carbon bond-forming reactions of putative α-carbonyl carbocation intermediates generated by Lewis acid- or silver-promoted ionizations of toluenesulfonate or halide leaving groups are described. This under-exploited mode of reactivity represents an 'umpolung' of conventional enolate chemistry, and enables C-C bond construction in both intra- and intermolecular contexts. Attempts to develop diastereoselective variants of this process using chiral ester and oxazolidinone-based auxiliaries are discussed.