1333067-48-3Relevant articles and documents
Macrolide compounds and methods and intermediates useful for their preparation
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Page/Page column 12, (2014/08/19)
The present invention provides intermediate compounds and synthetic methods that can be used to prepare complex cyclic compounds including macrolides. The invention also provides cyclic compounds that have useful biological properties such as antiinfectiv
Direct entry to erythronolides via a cyclic bis[allene]
Liu, Kai,Kim, Hiyun,Ghosh, Partha,Akhmedov, Novruz G.,Williams, Lawrence J.
supporting information; experimental part, p. 14968 - 14971 (2011/11/05)
The complexity and low tractability of antibiotic macrolides pose serious challenges to addressing the problem of resistance through semi- or total synthesis. Here we describe a new strategy involving the preparation of a complex yet tractable macrocycle